WOFAPS 2025 8th World Congress of Pediatric Surgery

Fatma Hadjou Belaid ¹, Hammou Benslimane ¹, Taher Guezzi ², Faycel Hamidou ¹, Hafida Haouari ¹

¹ Etablissement hospitalier spécialisé en pédiatrie de Canastel - Oran ­Algérie
² Centre hospitalo -universtaire de Belabess - Algérie

Prupose : To evaluate the efficacy and tolerance of botulinum toxin type A injection to control overactive bladder in cases of failure of anticholinergics .

Materials and Methods :Between 2020 and 2023, a sample of 30 patients aged 6 to 15 years were treated for bladder overactivity suggested by
involuntary contractions of the detrusor during filling, confirmed by urodynamics, resistant to anticholinergic. Patients were injected with botulinum toxin
type A, the result was évaluted on clinical symptoms 04 months post injection.

Results: 22 girls, 8 boys, reviewed for urinary symptoms including daytime incontinence (08 cases), urgency with nocturnal enuresis (10 cases),frequency of micturition exceeding 08 per day (09 cases), 09 recurrent urinary tract infections,06 constipation controlled before injection.The injected dose of (14 to 20 IU), at follow-up (46%) was clean, improvement in urinary frequency (38%), disappearance of enuresis (28%), improvement in urgency (27%). side’s effects are represented by 02 urinary retention benefiting from a permanent catheterization, 09 urinary infections, 04 pelvic pains, after 04 years, decrease in the duration of continence of 02 hours instead of 04 hours (02 cases).

Conclusions: By its effectiveness, low morbidity and stable results, Dysport has become an alternative safe for manage refractory overactive bladder in children in cases where anticholinergics have failed,thus avoiding any heavy and hard therapy.