WOFAPS 2025 8th World Congress of Pediatric Surgery

Liyang Ying, Xicheng Zhang, Xiangming Fan, Qiang Shu

Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children’s Regional Medical Center

Purpose: To analyze and report the outcomes of neonatal congenital heart disease (CHD) surgeries performed at our center over the past five years, providing a reference for the surgical treatment of critical neonatal CHD in China.

Method: A retrospective analysis was conducted on neonates (age <30 days at surgery) who underwent CHD surgery in our center between January 2020 and December 2024. Data on diagnoses, mortality, adverse events, and ECMO support were summarized. Normally distributed continuous variables were expressed as mean ± standard deviation (x̄ ± s), non-normally distributed variables as median, and categorical variables as percentages.

Result: Over the five-year period, 528 neonatal CHD surgeries were performed, including 241 cases requiring cardiopulmonary bypass and 115 cases involving low birth weight (≤2.5 kg). There were 296 male and 233 female patients, with a mean surgical age of 16.69 ± 8.73 days and a mean weight of 2.64 ± 0.94 kg. In-hospital mortality was 16 cases (3.0%). Excluding PDA, the top five diagnoses were TGA (58 cases), TAPVC (57 cases), CoA (48 cases), VSD (31 cases), and IAA (21 cases). Mortality rates were 10.5% for TAPVC, 9.5% for IAA, 8.6% for TGA, and 4.2% for CoA. Postoperative ECMO support was required in 29 cases, with 10 deaths, yielding an overall ECMO mortality rate of 34.5%.

Conclusion: The surgical success rate for neonatal CHD at our center over the past five years has approached internationally advanced levels. Notably, the mortality rate for critical neonatal CHD cases requiring ECMO support has declined annually, providing valuable experience and reference for neonatal surgical treatment in China.