Poster - 69
ASSESSMENT OF MALIGNANCY RISK OF THYROID NODULES IN CHILDREN
Sergey Minaev 1, Igor Gerasimenko 1, Oksana Iachnaia 1, Jennifer Martinez 2, Maria Bagdasaryan 1
1 Stavropol State Medical University
2 University of Santo Domingo
We present the results and clinical validation of the author's prognostic scale for assessing the oncological risk of thyroid nodules in children based on a combination of clinical, anamnestic, and ultrasound criteria. The scale combines a multifactorial approach, including anamnestic data, clinical symptoms, and highly informative ultrasound signs. Such an integral construction significantly increases the accuracy of risk assessment compared to the use of individual parameters. The study included patients aged 8 to 18 years, classified based on the results of clinical and morphological examination as follows: patients with benign thyroid nodules (n = 62) and children with thyroid cancer (n = 12). The control group consisted of clinically healthy children (n = 100). Intergroup statistical analysis, ROC analysis and assessment of the internal consistency of the scale were performed. The results obtained in the work showed the proposed scale's high sensitivity, specificity, and reliability. The proposed approach allows for primary screening covering various groups of the pediatric population. The scale provides for increased diagnostic accuracy, minimization of unnecessary invasive interventions, and improved routing of patients with thyroid lesions.