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TÜRKÇE
Poster - 58
Surgical Management of Inflammatory Myofibroblastic Tumors in Children with Bronchopulmonary Localization: A Single-Center Experience
Maxim Airapetyan 1, Oleg Topilin 2, Oleg Pikin 3, Olga Sukhodolskaya 4, Dmitry Morozov 5
1 Moscow Multidisciplinary Medical Center "Kommunarka" of the Moscow Department of Health
2 Russian Children's Clinical Hospital
3 Moscow Research Institute of Oncology named after P.A. Herzen
4 First Moscow State Medical University named after I.M. Sechenov (Sechenov University)
5 Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University
Purpose:
To present a clinical series of pediatric patients with inflammatory myofibroblastic tumors (IMFTs) of bronchopulmonary origin, highlighting diagnostic and therapeutic strategies for achieving optimal outcomes.
Materials and Methods:
Between 2017 and [current year], eight patients (aged 8–17 years; male-to-female ratio 7:1) with histopathologically confirmed IMFT were treated at our institution. Preoperative biopsy confirmed the diagnosis in six cases. Tumor localization included the trachea (n=1), left main bronchus (n=1), and pulmonary parenchyma (n=6). Surgical interventions comprised:
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Circular resection of the trachea/bronchi (n=2)
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Thoracoscopic lobectomy (n=2)
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Open thoracotomy lobectomy (n=1)
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Thoracoscopic anatomical segmentectomy (n=2).
Three-dimensional modeling and augmented reality were utilized for preoperative planning and intraoperative navigation.
Results:
All procedures were completed without intraoperative complications (operative time: 80–190 minutes). R0 resection (margin-negative) was achieved in all cases, with no instances of residual disease. During follow-up (1–3 years), no recurrences were observed.
Conclusions:
IMFTs of the bronchopulmonary system are rare in pediatric populations. Radical surgical excision with clear margins remains the cornerstone of treatment, ensuring long-term remission and preventing recurrence. Minimally invasive techniques, supported by advanced imaging technologies, offer a safe and effective approach for resection.